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  P Glycoprotein

Medical Dictionary
Definition of medical terminology for P Glycoprotein.
A 170 kD transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS.
It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).

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