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Accolate

Category: Drugs A
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Date: 06 Feb 2010
Definition of medical terminology for Patients.
A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
Of abrupt onset, in reference to a disease.
A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
Description: Zafirlukast is used by patients with mild-to-moderate asthma to decrease the symptoms of asthma and the number of acute asthma attacks.

Definition of medical terminology for Medicine.
A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
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Definition of medical terminology for Medicines.
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Definition of medical terminology for Infections.
Definition of medical terminology for Patients.
Definition of medical terminology for Infections.
Definition of medical terminology for Pregnant Women.
Definition of medical terminology for Pregnant Women.
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Biomonitoring of Environmental Status and Trends Program (U.S. Geological Survey)
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Definition of medical terminology for Medicines.
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An organic chemical in which one or more hydroxyl (OH) groups are attached to carbon (C) atoms in place of hydrogen (H) atoms.
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Definition of medical terminology for Medicine.
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A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
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In radiology, the amount of energy that is deposited in any material by ionizing radiation.
Definition of medical terminology for Meal on Wheels.
A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
Definition of medical terminology for Medicine.
Definition of medical terminology for Patients.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
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Nationwide Evaluation of X-ray Trends (CDRH)
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Definition of medical terminology for Medicine.
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A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
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A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways.
Definition of medical terminology for Doctor Patient Relation.
Definition of medical terminology for Medicine.
Not normal.
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Attention getting is not a simple automatic act.
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Attention getting is not a simple automatic act.
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However, this medicine should not be used to relieve an asthma attack that has already started.
This medicine is available only with your doctor`s prescription.


This product is available in the following dosage forms:



  • Tablet


Before Using


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Appropriate studies have not been performed on the relationship of age to the effects of zafirlukast in children up to 7 years of age. Safety and efficacy have not been established.


Geriatric


In studies, mild to moderate respiratory tract infections were more likely to occur in patients 55 years of age or older taking zafirlukast. It is not known whether these infections were caused by taking zafirlukast or by other factors.


Pregnancy













Pregnancy CategoryExplanation
All Trimesters B Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breastfeeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Drug Interactions


Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.



  • Erythromycin

  • Terfenadine

  • Theophylline

  • Warfarin


Other Interactions


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Proper Use


Zafirlukast is used to prevent asthma attacks. It is not used to relieve an attack that has already started. For relief of an asthma attack that has already started, you should use an inhaled medicine that works quickly. If you do not have another medicine to use for an attack or if you have any questions about this, check with your doctor .


Food may change the amount of zafirlukast that is absorbed . It should be taken on an empty stomach, 1 hour before or 2 hours after a meal .


To work properly, zafirlukast must be taken every day at regularly spaced times, even if your asthma seems better.


Dosing


The dose of this medicine will be different for different patients. Follow your doctor`s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.



  • For oral dosage form (tablets):

    • For asthma:

      • Adults and children 12 years of age and oldera€”20 milligrams (mg) two times a day.

      • Children between 7 and 11 years of agea€”10 mg two times a day.

      • Children younger than 7 years of agea€”Use and dose must be determined by your doctor .






Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions


You may be taking other medicines for asthma along with zafirlukast. Do not stop taking or reduce the dose of the other medicines, even if your asthma seems better, unless you are told to do so by your doctor .


This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed and have problems with sleep. If you, your child, or your caregiver notice any of these side effects, tell your doctor or your child`s doctor right away.


Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention .


Check with your doctor immediately if any of the following side effects occur:


Incidence not known



  • Attack, assault, or force

  • Attempts at killing oneself

  • Discouragement

  • Dry mouth

  • Fear or nervousness

  • Feeling sad or empty

  • Hyperventilation

  • Irregular heartbeats

  • Irritability

  • Lack of appetite

  • Loss of interest or pleasure

  • Restlessness

  • Seeing, hearing, or feeling things that are not there

  • Shakiness in the legs, arms, hands, or feet

  • Shortness of breath

  • Sleeplessness

  • Tiredness

  • Trembling or shaking of the hands or feet

  • Trouble with concentrating

  • Trouble with sleeping

  • Unable to sleep


Some side effects may occur that usually do not need medical attention . These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


Less common



  • Headache

  • Nausea


Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional .


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


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