Home » Drugs and Supplements A-Z » Drugs A

Abacavir, Lamivudine, and Zidovudine (Oral Route)

Category: Drugs A
Views: 155
Date: 06 Feb 2010
Definition of medical terminology for Medicines.
Definition of medical terminology for Human Immunodeficiency Virus.
A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell.
Definition of medical terminology for Infection.
Description: Abacavir, lamivudine, and zidovudine combination is used alone or together with other medicines to treat human immunodeficiency virus (HIV) infection.

A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell.
Anything that is not present at birth but develops some time later.
Definition of medical terminology for Deficiency Disease.
Definition of medical terminology for Syndrome.
The active form of zidovudine which is also known as AZT.
Definition of medical terminology for Infection.
The involuntary weight loss of 10% of baseline body weight plus either chronic diarrhea (two loose stools per day for more than 30 days) or chronic weakness and documented fever (for 30 days or more, intermittent or constant) in the absence of a concurrent illness or condition other than HIV infection that would explain the findings.
Definition of medical terminology for Medicine.
Definition of medical terminology for Slow Loris.
Definition of medical terminology for System A Transporter.
Definition of medical terminology for Health.
Disease due to infection with the human immunodeficiency virus (HIV).
Definition of medical terminology for Infection.
Definition of medical terminology for People with Disabilities.
Definition of medical terminology for Medicine.
Disease due to infection with the human immunodeficiency virus (HIV).
Definition of medical terminology for Infection.
Definition of medical terminology for Medicine.
Definition of medical terminology for Prescription.
Definition of medical terminology for Dosage Compensation.
Definition of medical terminology for Risks.
Definition of medical terminology for Medicine.
The hypersensitive response of the immune system of an allergic individual to a substance.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicines.
Definition of medical terminology for Health.
Definition of medical terminology for Foods, Enriched.
Definition of medical terminology for Medicine.
Definition of medical terminology for Decreased Bulbocavernosus Reflex.
Definition of medical terminology for Medicine.
Definition of medical terminology for Patients.
Definition of medical terminology for Body Sizes.
Definition of medical terminology for Medicine.
Definition of medical terminology for Elderly.
Definition of medical terminology for Elderly.
Definition of medical terminology for Patients.
Definition of medical terminology for Heart.
Definition of medical terminology for Patients.
Definition of medical terminology for Medicine.
A harmful or abnormal result.
Definition of medical terminology for Pregnant Women.
Definition of medical terminology for Pregnant Women.
Definition of medical terminology for Infant.
Definition of medical terminology for Risk.
Definition of medical terminology for Risks.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicines.
Definition of medical terminology for Medicines.
Definition of medical terminology for Medicines.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicines.
Definition of medical terminology for Risk.
Definition of medical terminology for Drugs.
Biomonitoring of Environmental Status and Trends Program (U.S. Geological Survey)
Definition of medical terminology for Medicines.
Definition of medical terminology for Medicines.
Definition of medical terminology for Medicines.
Definition of medical terminology for Food.
Definition of medical terminology for Food.
An organic chemical in which one or more hydroxyl (OH) groups are attached to carbon (C) atoms in place of hydrogen (H) atoms.
Definition of medical terminology for Tobacco.
Definition of medical terminology for Medicines.
Definition of medical terminology for Healthcare.
Definition of medical terminology for Medicine.
Definition of medical terminology for Tobacco.
Definition of medical terminology for Medical Assistance.
The emotional tone a person expresses.
Definition of medical terminology for Medicine.
Definition of medical terminology for Bone.
Definition of medical terminology for Marrow.
Definition of medical terminology for Disease.
Definition of medical terminology for Blood Pressure.
Definition of medical terminology for Gene.
Definition of medical terminology for Variation.
Definition of medical terminology for Risk.
Definition of medical terminology for Patients.
Definition of medical terminology for Medicine.
Definition of medical terminology for Doctor Patient Relation.
Safe Tables Our Priority
FDA Information Retrieval System
Definition of medical terminology for Medicine.
Definition of medical terminology for Medication Error.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicines.
Definition of medical terminology for Infection.
Definition of medical terminology for Medicines.
Definition of medical terminology for Medicines.
Biomonitoring of Environmental Status and Trends Program (U.S. Geological Survey)
Definition of medical terminology for Blood Air Barrier.
Definition of medical terminology for Planning.
Biomonitoring of Environmental Status and Trends Program (U.S. Geological Survey)
Definition of medical terminology for Doctor Patient Relation.
Definition of medical terminology for Medicine.
Definition of medical terminology for Pharmacy.
Definition of medical terminology for Doctor Patient Relation.
A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell.
Definition of medical terminology for Medicine.
A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
The practice of cutting tablets in half.
Definition of medical terminology for Medicine.
Definition of medical terminology for Patients.
Definition of medical terminology for Only Child.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medical Assistance.
Definition of medical terminology for Medicine.
Definition of medical terminology for Dosage Compensation.
Definition of medical terminology for Human Immunodeficiency Virus.
A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell.
Definition of medical terminology for Recommended Daily Allowance.
Nationwide Evaluation of X-ray Trends (CDRH)
Definition of medical terminology for Schedule.
Definition of medical terminology for Medicine.
Definition of medical terminology for Light.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Healthcare.
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Blood Tests.
Definition of medical terminology for Medicine.
The hypersensitive response of the immune system of an allergic individual to a substance.
Definition of medical terminology for Patients.
Definition of medical terminology for Medicine.
Definition of medical terminology for Lead.
Definition of medical terminology for Blood Pressure.
Definition of medical terminology for Death.
Safe Tables Our Priority
Definition of medical terminology for Medicine.
Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen includes a host of organs including the stomach, small intestine, colon, rectum, liver, spleen, pancreas, kidneys, appendix, gallbladder, and bladder. The word "abdomen" has a curious story behind it. It comes from the Latin "abdodere", to hide. The idea was that whatever was eaten was hidden in the abdomen.
Definition of medical terminology for Stomach.
Definition of medical terminology for Numbness.
Definition of medical terminology for Pain.
Definition of medical terminology for Pain.
Definition of medical terminology for Feet.
Definition of medical terminology for Feeling.
Medically known as hyperemesis gravidarum, this is excessive vomiting in early pregnancy.
Definition of medical terminology for Allergic Reactions.
A disease (also more commonly called the Churg-Straus syndrome) characterized by inflammation of the blood vessels in persons with a history of asthma or allergy.
Safe Tables Our Priority
Definition of medical terminology for Medicine.
Definition of medical terminology for Medicine.
Definition of medical terminology for Pharmacist.
Definition of medical terminology for Medicine.
The hypersensitive response of the immune system of an allergic individual to a substance.
Definition of medical terminology for Past Trend.
Definition of medical terminology for Medicine.
Definition of medical terminology for Lactic Acidosis.
Too much acid in the body, a distinctly abnormal condition resulting from the accumulation of acid or from the depletion of alkaline reserves.
Definition of medical terminology for Enlarged Liver.
Definition of medical terminology for Liver Abscess.
Definition of medical terminology for Medicines.
Pain in the belly (the abdomen). Abdominal pain can come from conditions affecting a variety of organs.
Definition of medical terminology for Feeling.
Definition of medical terminology for Muscle.
Definition of medical terminology for Skin Abnormalities.
Definition of medical terminology for Start Codon.
Definition of medical terminology for Infections.
Definition of medical terminology for Pneumonia.
Definition of medical terminology for Medicine.
Definition of medical terminology for Stomach.
Definition of medical terminology for Face.
Definition of medical terminology for Infection.
Definition of medical terminology for Breast.
Definition of medical terminology for Milk.
Definition of medical terminology for Medicine.
Definition of medical terminology for Risk.
Definition of medical terminology for Infection.
Definition of medical terminology for Blood Air Barrier.
Definition of medical terminology for Fluids, Amniotic.
Definition of medical terminology for Semen.
Biomonitoring of Environmental Status and Trends Program (U.S. Geological Survey)
Definition of medical terminology for Body Fluids.
Definition of medical terminology for People with Disabilities.
Definition of medical terminology for Partner Abuse.
Definition of medical terminology for Latex.
Definition of medical terminology for Polyurethane.
Definition of medical terminology for Semen, Frozen.
Definition of medical terminology for Blood Air Barrier.
Definition of medical terminology for Needles.
Definition of medical terminology for Needles.
Definition of medical terminology for Doctor Patient Relation.
Definition of medical terminology for Medicines.
Definition of medical terminology for Doctor Patient Relation.
Definition of medical terminology for Prescription.
Definition of medical terminology for Medicines.
The use of vitamins to prevent or cure disease.
Definition of medical terminology for Medicine.
Attention getting is not a simple automatic act.
Relating to the abdomen, the belly, that part of the body that contains all of the structures between the chest and the pelvis. The abdomen includes a host of organs including the stomach, small intestine, colon, rectum, liver, spleen, pancreas, kidneys, appendix, gallbladder, and bladder. The word "abdomen" has a curious story behind it. It comes from the Latin "abdodere", to hide. The idea was that whatever was eaten was hidden in the abdomen.
Definition of medical terminology for Stomach.
Definition of medical terminology for Numbness.
Definition of medical terminology for Pain.
Definition of medical terminology for Pain.
Definition of medical terminology for Feet.
Definition of medical terminology for Feeling.
Liquid waste.
Special Products On-Line Tracking System (CDER)
Definition of medical terminology for Bleeding.
Attention getting is not a simple automatic act.
Definition of medical terminology for Medicine.
Definition of medical terminology for Health.
Definition of medical terminology for Health.
Definition of medical terminology for Patients.
Definition of medical terminology for Healthcare.
Definition of medical terminology for Professional Activity Studies.

HIV is the virus that causes acquired immune deficiency syndrome (AIDS).


Abacavir, lamivudine, and zidovudine combination will not cure or prevent HIV infection or the symptoms of AIDS . This medicine helps keep HIV from reproducing, and appears to slow down the destruction of the immune system . This may help delay the development of serious health problems usually related to AIDS or HIV infection. Abacavir, lamivudine, and zidovudine combination will not keep you from spreading HIV to other people . People who receive this medicine may continue to have other problems usually related to AIDS or HIV infection.


This medicine is available only with your doctor`s prescription.


This product is available in the following dosage forms:



  • Tablet


Before Using


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Abacavir, lamivudine, and zidovudine combination contains a fixed amount of each medicine that cannot be decreased . Therefore, this medicine is not recommended for patients who weigh less than 40 kilograms (88 pounds) because the amounts of abacavir, lamivudine, and zidovudine in this product cannot be adjusted for smaller body sizes.


Geriatric


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of this medicine in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems which may require caution and an adjustment in the dose for patients receiving this medicine.


Pregnancy













Pregnancy CategoryExplanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Drug Interactions


Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.



  • Dapsone

  • Doxorubicin Hydrochloride

  • Flucytosine

  • Ganciclovir

  • Interferon Alfa

  • Pyrazinamide

  • Pyrimethamine

  • Ribavirin

  • Stavudine

  • Vinblastine

  • Vincristine

  • Vincristine Liposome

  • Zalcitabine


Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.



  • Acetaminophen

  • Interferon Beta-1a

  • Methadone

  • Nelfinavir

  • Probenecid

  • Rifabutin

  • Rifampin

  • Rifapentine

  • Tipranavir

  • Valproic Acid


Other Interactions


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:



  • Blood problems (e.g., anemia, decreased bone marrow production) or

  • Diabetes or

  • Heart disease or

  • Hepatitis B, history of or

  • Hepatitis C, history of or

  • High blood pressure or

  • High cholesterol or

  • Myopathy (muscle weakness)aUse with caution. May make these conditions worse.



  • Genetic condition (e.g., gene variation called HLA-B*5701)aThis condition may increase the risk for serious and life-threatening side effects.



  • Kidney disease, severe or

  • Liver diseaseaShould not be used in patients with these conditions.


Proper Use


Take this medicine exactly as directed by your doctor . Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not start or stop taking abacavir, lamivudine, and zidovudine combination without checking with your doctor first.


This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.


This medicine will be given together with other medicines for HIV infection. Take all of the medicines your doctor gives you at the right time of day. These medicines work best when there is a constant amount in the blood . To help keep the amount constant, do not miss any doses. If you need help in planning the best times to take your medicines, check with your doctor .


When your supply of this medicine runs low, get more from your pharmacy or from your doctor . The amount of virus in your blood may increase if the medicine is stopped, even for a short time. The virus may develop resistance to this medicine and be harder to treat.


Only take medicine that your doctor has prescribed specifically for you. Do not share your medicine with others.


Abacavir, lamivudine, and zidovudine combination contains a fixed amount of each medicine in the tablet .


Dosing


The dose of this medicine will be different for different patients. Follow your doctor`s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.



  • For oral dosage form (tablets):

    • For human immunodeficiency virus (HIV) infection:

      • Adults, teenagers, and children who weigh more than 40 kilograms (kg) (88 pounds)a300 milligrams (mg) of abacavir, 150 mg of lamivudine, and 300 mg of zidovudine (equal to one tablet) two times a day.

      • Adults, teenagers, and children who weigh 40 kg (88 pounds) or lessaUse is not recommended .






Missed Dose


If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Ask your healthcare professional how you should dispose of any medicine you do not use.


Precautions


It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Blood tests may be needed to check for unwanted effects.


This medicine may cause a severe allergic reaction in some patients. This reaction usually occurs within 6 weeks after the medicine is started, but may occur at any time. If untreated, it can lead to severe low blood pressure and even death. Stop taking this medicine and check with your doctor immediately if you notice abdominal or stomach pain; cough; diarrhea; fever; headache; nausea; numbness or tingling of the face, feet, or hands; pain in the joints; pain in the muscles; shortness of breath; skin rash; sore throat; swelling of the feet or lower legs; unusual feeling of discomfort or illness; unusual tiredness or weakness; or vomiting .


When you begin taking this medicine, you will be given a warning card which describes symptoms of severe allergic reactions that may be caused by abacavir, lamivudine, and zidovudine combination. The warning card also provides information about how to treat these allergic reactions. For your safety, you should carry the warning card with you at all times.


If you must stop using abacavir because of an allergic reaction, you should never use the medicine again. Return the unused medicine to your doctor or pharmacist. A worse reaction, possibly even death, can occur if you use the medicine again. Tell your doctor right away if you have ever taken abacavir, especially if you have experienced an allergic reaction to it in the past .


Two rare but serious reactions to this medicine are lactic acidosis (too much acid in the blood) and liver toxicity, which includes an enlarged liver . These are more common if you are female, very overweight (obese), or have been taking anti-HIV medicines for a long time. Call your doctor right away if you or your child have more than one of these symptoms: abdominal discomfort or cramping; dark urine; decreased appetite; diarrhea; general feeling of discomfort; light-colored stools; muscle cramping or pain; nausea; unusual tiredness or weakness; trouble breathing; vomiting; or yellow eyes or skin .


When you or your child start taking HIV medicines, your immune system may get stronger. If you have infections that are hidden in your body (e.g., pneumonia or tuberculosis), you may notice new symptoms when your body tries to fight them. If this occurs, tell your doctor right away.


This medicine may cause you or your child to have excess body fat. Tell your doctor right away if you notice changes in your body shape, including an increased amount of body fat in the neck or upper back, face, around the chest, or stomach area. You might also lose fat from your legs, arms, or face.


You should not breastfeed if you have HIV or AIDS, because you may give the infection to your baby through your breast milk.


This medicine does not decrease the risk of transmitting the HIV infection to others through sexual contact or by contamination through blood . HIV may be spread to others through infected body fluids, including blood, vaginal fluid, or semen. If you are infected, it is best to avoid any sexual activity involving an exchange of body fluids with other people . If you do have sex, always wear (or have your partner wear) a condom (arubbera). Only use condoms made of latex or polyurethane and use them every time you have contact with semen, vaginal secretions, or blood . Also, do not share needles with anyone or use dirty needles. If you have any questions about this, check with your doctor .


Do not take other medicines unless they have been discussed with your doctor . This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.


Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention .


Check with your doctor immediately if any of the following side effects occur:


More common



  • Chills


Less common



  • Hypersensitivity reaction, including abdominal or stomach pain; cough; diarrhea; fever; headache; nausea; numbness or tingling of the face, feet, or hands; pain in the joints; pain in the muscles; shortness of breath; skin rash; sore throat; swelling of the feet or lower legs; unusual feeling of discomfort or illness; unusual tiredness or weakness; or vomiting

  • Muscle weakness

  • Pale skin

  • Yellow eyes or skin


Rare



  • Black, tarry stools

  • Blood in the urine or stools

  • Pinpoint red spots on the skin

  • Unusual bleeding or bruising


Some side effects may occur that usually do not need medical attention . These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


More common



  • Bone pain

  • Loss of appetite

  • Sleeplessness

  • Trouble sleeping


Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional .


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Tags: Trizivir
 

General Search


Last medical tags:


Torisel, temsirolimus, Inlyta, chronic myeloid leukemia, bosutinib, Inlyta, renal cell carcinoma, kidney cancer, myelin, Tysabri, natalizumab, brain infection, progressive multifocal leukoencephalopathy, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, thoracic aortic transection, endovascular graft, methotrexate, Voraxaze, cancer chemotherapy drug, glucarpidase, Adcetris, bleomycin, multifocal leukoencephalopathy, CardioGen-82, radiation, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, FDA, New drugs approval 2012, drugs approved by FDA, raltegravir, Isentress, antiretroviral medicines, Theravance, Relovair, asthma, fluticasone, bronchitis, neuromuscular disease, SMA, muscle atrophy, Resolor, prokinetic, prucalopride, ADHD, psychiatric behavioural disorder, Venvanse, lisdexamfetamine dimesylate, type 2 diabetes mellitus, Actoplus Met XR, pioglitazone, Mylan, Eprosartan Mesylate Tablets, Teveten, antimicrobials, cephapirin, cephalosporin, teriflunomide, Rebif, alanine aminotransferase levels, flu-like symptoms, multiple sclerosis, electrical pulses, implantable pulse generator, Precision Plus Spinal Cord Stimulator, genetic blood clotting disorder, hemophilia A, Advate, bleeding episodes, heart failure, heart transplantation, Pediatric Medical Device Safety, pulsatile cardiac assist device, selective serotonin reuptake inhibitor, SSRI, pulmonary hypertension,
» All tags  
Sitemap